“Pharmacogenomics: Paving the path to Translational Medicine”
DIVANI Apollon Palace and Spa, 15-17 October 2009, Athens, Greece
We are very pleased to invite you to attend the 2009 Golden Helix Symposium: Pharmacogenomics: Paving the path to personalized medicine October 15th-17th, 2009 Divani Apollon Palace and Spa hotel, Athens, Greece. Pharmacogenomics is gaining momentum in modern medical practice. Recognizing the challenges that currently emerge for molecular medicine in the post-genomic era, the Golden Helix Symposium on Pharmacogenomics includes lectures by more than 20 international leading scientists in the field and covers all aspects of this exciting new discipline, including, Warfarin, Cancer pharmacogenomics, Pharmacogenomics on neuropsychiatric (e.g. epilepsy, schizophrenia) & other disorders e.g. blood diseases, cardiovascular and connective tissue disorders, adverse effects, databases, etc. We are committed to setting the highest standard symposia in the field of human genomics and we look forward to welcoming you to Athens.
The 2009 Golden Helix Symposium Organizing Committee
Organized by:
Endorsed by:
WelcomeVenueSpeakersScientific ProgramSponsorsGallery“Pharmacogenomics: Paving the path to Translational Medicine”
DIVANI Apollon Palace and Spa, 15-17 October 2009, Athens, Greece
We are very pleased to invite you to attend the 2009 Golden Helix Symposium: Pharmacogenomics: Paving the path to personalized medicine October 15th-17th, 2009 Divani Apollon Palace and Spa hotel, Athens, Greece. Pharmacogenomics is gaining momentum in modern medical practice. Recognizing the challenges that currently emerge for molecular medicine in the post-genomic era, the Golden Helix Symposium on Pharmacogenomics includes lectures by more than 20 international leading scientists in the field and covers all aspects of this exciting new discipline, including, Warfarin, Cancer pharmacogenomics, Pharmacogenomics on neuropsychiatric (e.g. epilepsy, schizophrenia) & other disorders e.g. blood diseases, cardiovascular and connective tissue disorders, adverse effects, databases, etc. We are committed to setting the highest standard symposia in the field of human genomics and we look forward to welcoming you to Athens.
The 2009 Golden Helix Symposium Organizing Committee
Organized by:
Endorsed by:
2009 Golden Helix Symposium Venue
The venue of the 2009 Golden Helix Symposium is the DIVANI Apollon Palace and Spa*****.
Divani Apollon Palace and Spa is a member of the Leading hotels of the world. This is a luxury beach resort in Athens situated in the exclusive area of Vouliagmeni, just 18km from the city centre. Guests enjoy, the pleasure of a private beach and an award winning Spa, the only one offering Thalassotherapy in the whole Attica region and one of the best Thalassotherapy centers in the Meditteranean.
Divani Apollon Palace and Spa is an excellent hotel for both leisure and business and offers quiet luxury at the prestigious Athenian Riviera.
Organizing committee
George P. Patrinos; University of Patras, Department of Pharmacy, Patras, Greece
Federico Innocenti; University of Chicago, Department of Medicine, Chicago, IL, USA
Invited Speakers
Hadi Abderrahim, Switzerland
Maria J Arranz, United Kingdom
Mara Becker, USA
Sotiria Boukouvala, Greece
Maria L Brandi, Italy
Evangelos Briasoulis, Greece
Paul Cordopatis, Greece
Norman Delanty, Ireland
Panos Deloukas, United Kingdom
Rafal Dziadziuszko, Poland
Argiris Efstratiadis, Greece
Michel Eichelbaum, Germany
Acchileas Gravanis, Greece
Laura Hodges, USA
Federico Innocenti, USA
Al Jorgensen, United Kingdom
David Josephy, Canada
Farhad Kamali, United Kingdom
Panagoula Kollia, Greece
Sefi Kronenberg, Israel
Lawrence Lesko, USA
Evangelos Manolopoulos, Greece
Sharron Marsh, USA
Miko Niemi, Finland
Andreas Papapetropoulos, Greece
George P. Patrinos, Greece
Anders Rane, Sweden
Allan Rettie, USA
Alessio Squassina , Italy
Nikos Stefanis, Greece
Eric Thervet, France
Antonis Tsarbopoulos, Greece
Asterios Tsiftsoglou, Greece
Ron H. van Shaik, The Netherlands
Vasilis Vasiliou V, USA
Scientific Program
Day 1 – October 15, 2009
10:00-13:30: Registration
13:30-14:00: Welcome Addresses
Session 1 INTRODUCTION (Chairpersons: Cordopatis P, Papapetropoulos A)
14:00-14:10: George Patrinos (Patras, Greece)
Translation of genetic knowledge into clinical practice: The expectations and realities of personalized medicines
14:10-14:30: Federico Innocenti (Chicago, IL, USA)
Pharmacogenomics: an Odyssey
14:30-15:00: Laura Hodges (USA)
PharmGKB: The Pharmacogenomics Knowledge Base
COFFEE BREAK
Session 2 – TRANSLATION OF PHARMACOGENOMICS INTO CLINICAL PRACTICE: THE WARFARIN PARADIGM (Chairpersons: Gravanis A, Kollia P)
15:15-15:45: Allan Rettie (Seattle, WA, USA)
Pharmacogenetics of vitamin K antagonists and resistance to anticoagulants
15:45-16:15: Panos Deloukas (Oxford, United Kingdom)
A whole genome scan for polymorphisms influencing warfarin dosing
16:15-16:45: Farhad Kamali (United Kingdom)
The International Warfarin Pharmacogenetics Consortium
16:45-17:15: Anders Rane (Sweden)
Warfarin pharmacogenomics – Translation into clinical practice
1st Keynote speech (Chairperson: Innocenti F)
17:20-18:00: Michel Eichelbaum (Germany)
Pharmacogenomic-guided drug therapy: Where do we stand in 2009
Welcome cocktail
EVENING FREE
Day 2 – October 16th, 2009
Session 3 – CANCER PHARMACOGENOMICS (Chairpersons: Efstratiadis A, Briasoulis E)
08:30-09:00: Rafal Dziadziuszko (Poland)
Response to EGFR inhibitors: a paradigm for integrating germline and somatic molecular determinants
09:00-09:30 Ron van Shaik (Rotterdam, the Netherlands)
Gene variants in tamoxifen metabolizing enzymes CYP2D6 and CYP2C19 predict breast cancer endocrine therapy outcome
09:30-10:00: Sharon Marsh (USA)
Irinotecan pharmacogenomics
10:00-10:30: Federico Innocenti (Chicago, IL, USA)
Early experience with genome-wide association studies in cancer chemotherapy
COFFEE BREAK
Session 4 – PHARMACOGENETICS IN NEUROPSYCHIATRIC DISEASES (Chairpersons: Vizirianakis IS, Stefanis N)
11:00-11:30: Maria Arranz (London, United Kingdom)
Pharmacogenetics and critical candidate genes involved in drug response for schizophrenia
11:30-12:00: Sefi Kronenberg (Jerusalem, Israel)
Pharmacogenetics of anti-depressants
12:00-12:30: Norman Delanty (Galway, Ireland)
Pharmacogenomics for epilepsy treatment
12:30-13:00: Alessio Squassina (Cagliari, Italy)
Pharmacogenomics of the response to mood stabilizers in bipolar disease
2nd Keynote speech (Chairperson: Patrinos GP)
13:00-13:45: Lawrence Lesko (USA)
Level of evidence to validate pharmacogenetic biomarkers
LUNCH BREAK
AFTERNOON: SOCIAL EVENT (for guest speakers)
Visit to the new Acropolis Museum (transportation will be provided to and from the hotel)
PARALLEL SCIENTIFIC SESSION (in Greek):
ROUND TABLE: The Greek experience of translational medicine
20:00: Official Dinner Mythos of the Sea Restaurant
Dress code: Smart casual
Day 3 – October 17, 2009
Session 5 – PHARMACOGENOMICS OF OTHER DISEASES (Chairperson: Tsarbopoulos A)
08:30-09:00: George P. Patrinos (Patras, Greece)
Pharmacogenomics of hemoglobinopathies
09:00-09:30: Maria-Luisa Brandi (Italy)
Pharmacogenomics of bone treatments
09:30-10:00: Eric Thervet (France)
Impact of heritablegenetic variability on renal transplantation
10:00-10:30: Mikko Niemi (Finland)
Statin pharmacogenomics for cardiovascular patients
10:30-11:00: Vassilis Vassiliou (USA)
Pharmacogenomics: Aldehyde Dehydrogenases in human disease
COFFEE BREAK
Session 6 – ADVERSE DRUG REACTIONS (Chairpersons: Manolopoulos N, Boukouvala S)
11:30-12:00: Al Jorgensen (United Kingdom)
Risk modeling strategies for pharmacogenetic studies
12:00-12:30: Mara Becker (USA)
Identifying genomic causes of Adverse Drug Reactions in children
12:30-12:50: Closing remarks Future meeting
Meeting ends
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