“Advancing Personalized Medicine to the Clinic”
25–29 September 2024
Dolphin Bay Resort hotel, Syros island, Greece
We are pleased to announce the 2024 Golden Helix Summer School that will be held in the island of Syros, Greece, the capital of the Cyclades islands in the Aegean archipelago. The 2024 Golden Helix Summer School will be organized in September 2024 and the theme of the Summer School will be “Advancing Personalized Medicine to the Clinic” and will revolve around the application of the most important disciplines of Genomic Medicine, such as Pharmacogenomics, Genome informatics, Public Health Pharmacogenomics, and economic evaluation in genome-guided interventions.
Also, as with previous events, we have included in the scientific program of this 2024 Golden Helix Summer school a career development and interactive sessions, where members of the Faculty will engage into lively discussions with the summer school participants about issues related to career advancement and key topics related to the theme of this meeting, respectively.
Apart from the high quality scientific program, the 2024 Golden Helix Summer School offers an attractive social program that includes a visit to the Apollo Theater in Hermoupolis, the renowned townhall and a traditional farewell dinner, allowing participants to get to know each other in a very informal way.
We have made every effort to minimize the registration fees to encourage participation of researchers from lower-income countries.
We are looking forward to welcoming you to Syros, Greece next September and to a very fruitful and stimulating conference.
The 2024 Golden Helix Summer School Organizing Committee
Co-organized by:
Under the auspices of:
About
Venue
Invited Speakers
Scientific Program
Logistics Information
Sponsors
Registration with an abstract
Registration without an abstract
Gallery
2024 Golden Helix Summer School, Syros Island, Greece
“Advancing Personalized Medicine to the Clinic”
25-29 September 2024
Dolphin Bay Resort hotel, Syros island, Greece
We are pleased to announce the 2024 Golden Helix Summer School that will be held in the island of Syros, Greece, the capital of the Cyclades islands in the Aegean archipelago. The 2024 Golden Helix Summer School will be organized in September 2024 and the theme of the Summer School will be “Advancing Personalized Medicine to the Clinic” and will revolve around the application of the most important disciplines of Genomic Medicine, such as Pharmacogenomics, Genome informatics, Public Health Pharmacogenomics, and economic evaluation in genome-guided interventions.
Also, as with previous events, we have included in the scientific program of this 2024 Golden Helix Summer school a career development and interactive sessions, where members of the Faculty will engage into lively discussions with the summer school participants about issues related to career advancement and key topics related to the theme of this meeting, respectively.
Apart from the high quality scientific program, the 2024 Golden Helix Summer School offers an attractive social program that includes a visit to the Apollo Theater in Hermoupolis, the renowned townhall and a traditional farewell dinner, allowing participants to get to know each other in a very informal way.
We have made every effort to minimize the registration fees to encourage participation of researchers from lower-income countries.
We are looking forward to welcoming you to Syros, Greece next September and to a very fruitful and stimulating conference.
The 2024 Golden Helix Summer School Organizing Committee
Co-organized by:
Under the auspices of:
The venue of the 2024 Golden Helix Summer School is the Dolphin Bay Resort hotel, situated in an ideal location in the bay of Galissas, by the seaside. Galissas is the most popular touristic destination. Galissas is located in a protected bay on the west coast of the island, which together with Danakos, a small and quiet farming village, number around 500 inhabitants. Galissas beach is long, with shallow-waters, and lined with tamarisk trees and has been awarded the blue-flag by the EU. There are various water sport activities. Area landmarks are the hill and church of Agia Pakou, immediately adjacent to the Dolphin Bay hotel, the small harbor with a quaint stone pier, the beach of Armeos, the large cave of Agios Stefanos with the water springs, as well as the chapels of Agios Mamas and Agios Kyrikos, the oldest church in Syros.
About Syros
Syros is the administrative center of Cyclades islands and is just 80 nautical miles from Athens. In Syros, the unique historical path, cultural wealth and imposing natural environment nicely blend. The island harmoniously combines the cosmopolitan and the traditional, the medieval with the modern urban, the Cycladic with the neoclassic, and the catholic with the Greek Orthodox historical tradition.
In Syros, there are more than 20.000 inhabitants, constituting the largest island of the Cyclades. Ermoupolis is the capital of Syros and of the Cyclades islands, a city that fascinates the visitor from the first moment he enters the harbor, with its breathtaking two hills that dominate the city, with the Catholic church of Saint George and the Greek Orthodox church of Resurrection at the top of each hill, and the impressive neoclassical mansions, built around the big natural harbor of the east coast of the capital city.
Created during the 1821 Greek revolution, Ermoupolis developed quickly into a big trade centre between east and west. The name Ermoupolis was adopted in 1826, dedicated to the kerdoos Ermis (Hermes the profitable). As the time went by, industries, workshops and Neorion shipyards were created in the city, leading to the economic development of Ermoupolis and to a cultural blossoming. This is also reflected in the architecture of the city, where the style created, conforms with the beginning of romantic classicism and is strongly influenced by western models.
Organizing Committee
George P. PATRINOS, Patras, Greece
Sonja PAVLOVIC, Belgrade, Serbia
Branka ZUKIC Belgrade, Serbia
Confirmed Speakers
Keynote Speakers
Marios Kambouris, Doha, Qatar
Harald Schmidt, Maastricht, The Netherlands
Ron H. van Schaik, Rotterdam, The Netherlands
Marc S. Williams, Danville, PA, USA
Plenary Speakers
Carlos Alejandro Díaz Tufinio, Mexico City, Mexico
Diego Forero, Bogota, Colombia
Cerissa French, Oxford, UK
Kariofyllis Karamperis, Patras, Greece
Stephan Kiefer, Saarland, Germany
Nikola Kotur, Belgrade, Serbia
Thorsten Lehr, Saarbrucken, Germany
Christina Mitropoulou, London, UK
Myrsini Ouzounelli, London, UK
George P. Patrinos, Patras, Greece
Sonja Pavlovic, Belgrade, Serbia
Yannis Pollalis, Piraeus, Greece
Gad Rennert, Haifa, Israel
Biljana Stankovic, Belgrade, Serbia
Vasilis Xirafas, Patras, Greece
Branka Zukic, Belgrade, Serbia
SCIENTIFIC PROGRAM
Tuesday 24 September 2024
19:00 – 20:00 Arrival and Registration
Wednesday 25 September 2024
12:00 – 14:30 Arrival and Registration
14:30 – 17:00 SESSION 1 – Moderator: George P. Patrinos
14:30 – 15:00 Introductions
Christianna Papitsi, Deputy Mayor for Tourism – Municipality of Syros-Ermoupolis, Greece
Welcome address
Branka Zukic – Institute of Molecular Genetics and Genetic Engineering, Belgrade, Republic of Serbia
Welcome address, PharmGenHub project
George P. Patrinos – University of Patras Department of Pharmacy, Patras, Greece
Ten years Golden Helix Summer Schools
15:00 – 16:00 Keynote Lecture 1
Marios Kambouris, Sidra Medicine, Department of Pathology & Laboratory Medicine, Division of Genetics, Doha, Qatar
Genomic Diagnostics in the Era of Personalized Precision Medicine
16:00 – 16:30 Oral presentations 1 – Moderator: George P. Patrinos
16:00 – 16:05 OP1. Cost-utility analysis of pharmacogenomics-guided tacrolimus treatment in Austrian kidney transplant recipients participating in the U-PGx PREPARE study
Vasileios Fragoulakis, Margarita-Ioanna Koufaki, Candace Joefield-Roka, Gere Sunder-Plassmann, Christina Mitropoulou
16:05 – 16:10 OP2. Economic evaluation of pharmacogenomic-guided antiplatelet treatment in Spanish patients suffering from acute coronary syndrome participating in the U-PGx PREPARE study
Margarita-Ioanna Koufaki, Vasileios Fragoulakis, Xando Díaz-Villamarín, Kariofyllis Karamperis, Cristina L. Dávila-Fajardo, Konstantinos Z. Vasileiou, George P. Patrinos, Christina Mitropoulou
16:10 – 16:15 OP3. Florine M. Wiss, Christian D. Krieg, Samuel S. Allemann, Henriette E. Meyer zu Schwabedissen, and Markus L. Lampert
CYP2D6 Phenotype as a Predictor of Adverse Drug Reactions in Patients Treated with Trazodone: Insights from an Observational Pharmacogenetic Study (online)
16:15 – 16:30 Q&A session
16:30 – 17:00 George P. Patrinos – University of Patras Department of Pharmacy, Patras, Greece, Editor-In-Chief, The Pharmacogenomics Journal (Nature Publishing Group)
Compiling a scientific article: From an author’s, reviewer and Editor-in-Chief’s perspective
17:00 – 19:30 Free time
19:30 – 21:00 Welcome cocktail – Networking
Thursday 26 September 2024
08:30 – 10:00 Breakfast
10:00 – 12:30 SESSION 2 – Moderator: Branka Zukic
10:00 – 10:30 Branka Zukic – Institute of Molecular Genetics and Genetic Engineering, Belgrade, Republic of Serbia
Next-generation genomics technologies for the advancement of personalized medicine
10:30 – 11:00 Biljana Stankovic – Institute of Molecular Genetics and Genetic Engineering, Belgrade, Republic of Serbia
Artificial intelligence in genomics and personalized medicine
11:00 – 11:30 Cerissa French – Oxford Nanopore Technologies, Oxford, UK
Corporate Lecture:
11:30 – 12:30 Keynote lecture 2
Harald Schmidt – University of Maastricht, the Netherlands
Systems medicine for network pharmacology and drug repurposing
12:30 – 14:00 Lunch break
14:00 – 14:40 Gad Rennert – National Israeli Academy of Scientific Medicine and B. Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
Testing the genomic medicine paradigm in a primary care practice
14:40 – 16:10 Workshop 2
PharmGenHub workshop: Bioinformatics tools for next-generation sequencing analysis in pharmacogenomics (demonstration)
Led by Nikola Kotur – Institute of Molecular Genetics and Genetic Engineering, Belgrade, Republic of Serbia
16:10 – 17:00 Oral presentations 2 – Moderator: Nikola Kotur
16:10 – 16:15 OP4. Anna Bollinger, Chiara Jeiziner, Henriette E. Meyer zu Schwabedissen, Kurt E. Hersberger, Samuel S. Allemann, Céline K. Stäuble
Systemic adverse drug reactions from ophthalmic timolol in a CYP2D6 homozygous *4 allele carrier (online)
16:15 – 16:20 OP5. Ioanna Poulida, George Mantzouranis, Vasileios Kostopoulos, George P. Patrinos
Development of a portable molecular biology and genetics laboratory for Personalized Medicine and Therapeutics
16:20 – 16:25 OP6. Point-of-need prompt molecular diagnosis: the fusion of minimalistic extraction protocols and portable instrumentation (online)
Manousos E. Kambouris, Stavroula Goudoudaki, Zoe Kordou, Stavroula Siamoglou, Yiannis Manoussopoulos, George P. Patrinos
16:25 – 16:30 OP7. Ion Channels as Biomarkers in Breast and Cervical Cancer
Agisilaos Balatsoukas, Diomedes E. Logothetis
16:30 – 16:35 OP8. Paola Tesolin, Giuseppe Giovanni Nardone, Alessandro Pecori, Aurora Santin, Lara Emily Rosso, Giulia Pianigiani, Beatrice Spedicati, Giorgia Girotto
Whole genome sequencing (WGS) in Italian genetic isolates: New insight into the CYP2D6 gene
16:35 – 16:40 OP9. Antonella Muzzo, Matteo Bramuzzo, Giulia Zudeh, Martina Franzin, Ute Hofmann, Elisa Lazzari, Germana Meroni, Matthias Schwab, Giuliana Decorti, Gabriele Stocco, Marianna Lucafò
Inflammatory bowel disease patient-derived organoids for personalized medicine: new insight on the mechanism of action of thiopurines
16:40 – 16:45 OP10. Association of ABCB1 and PXR genetic variants with Tacrolimus dose requirements in Greek renal transplant recipients
Anna Tsironi, Styliani-Christina Koukidi, Korina, Anne John, Alexandra Gerou, Aikaterini Kotzamouratoglou, Anastasia Kalliga, Ioannis Lakoumentas, Spyridon Gerou, Stavroula Siamoglou, Bassam R. Ali, George P. Patrinos
16:45 – 17:00 Q&A session:
17:00 – 19:30 Free time
19:30 – 21:00 Dinner
Friday 27 September 2024
08:30 – 10:00 Breakfast
10:00 – 12:30 SESSION 3 – Moderator: Diego Forero
10:00 – 10:30 Kariofyllis Karamperis – University of Patras Department of Pharmacy, Patras, Greece
Population Pharmacogenomics
10:30 – 11:00 Carlos Alejandro Díaz Tufinio – Department of Bioengineering, Tecnológico de Monterrey, Mexico City, Mexico
Lessons from the New to the Old Pharmacology: Implementation of Pharmacogenetics in Bioequivalence and Pharmacokinetics Trials
11:00 – 12:30 Workshop 3 NCODA workshop – Precision Oncology
11:00 – 11:30 Branka Zukic – Institute of Molecular Genetics and Genetic Engineering, Belgrade, Republic of Serbia
Thiopurine pharmacogenomics in pediatric acute lymphoblastic leukemia: On the way to personalized medicine
11:30 – 12:30 Diego Forero – Facultad de Ciencias de la Salud y del Deporte, Fundación Universitaria del Área Andina, Bogota, Colombia
Advanced online tools for analysis of genome-wide expression data for precision oncology (NCBI GEO, Array Express, BioGPS, GEO2R, ExpressAnalyst, imaGEO)
12:30 – 14:00 Lunch break
14:00 – 14:30 Thorsten Lehr – University of Saarland, Saarbrucken, Germany
Drug-drug-gene interactions: The SafePolyMed paradigm
14:30 – 16:00 Workshop 4
SafePolyMed workshop (demonstration)
Led by Stephan Kiefer – Fraunhofer Institute For Biomedical Engineering, Germany
16:00 – 17:00 Keynote lecture 3
Ron H. van Schaik – Erasmus University Medical Center, Department of Clinical Chemistry, Rotterdam, the Netherlands
Genome-guided therapeutics in the clinic: Examples and applications
17:00 – 19:30 Free time
19:30 – 21:00 Dinner
Saturday 28 September 2024
08:30 – 10:00 Breakfast
10:00 – 12:30 SESSION 4 – Moderator: Vasilios Xirafas
10:00 – 10:30 Christina Mitropoulou – The Golden Helix Foundation, London, UK
Economic evaluation in genome-guided therapeutic interventions
10:30 – 11:00 Myrsini Ouzounelli – MYO Health, London, UK
Market Access and genetic biomarkers
11:00 – 11:30 Konstantinos Vasileiou – University of Patras Department of Pharmacy, Patras, Greece
Marketing approaches in personalized medicine
11:30 – 12:00 Sonja Pavlovic – Institute of Molecular Genetics and Genetic Engineering, Belgrade, Republic of Serbia
Establishing regional excellence in personalized medicine: The SERBORDIS-Inn and PharmGenHub success stories
12:00 – 12:30 Yannis Pollalis – University of Piraeus, Piraeus, Greece
Personal Branding: Identifying and Communicating Our Value and Growth Potential
12:30 – 14:00 Lunch break
14:00 – 14:30 Vasilios Xirafas – University of Patras Department of Pharmacy, Patras, Greece
Genethics: Ethical perspectives in Personalized Medicine
14:30 – 15:30 Workshop 5
Ethical and philosophical approaches in genome-guided therapeutics: Case studies
Led by Vasilios Xirafas
15:40 Departure for Ermoupolis walking guided tour
16:00 – 18:00 Ermoupolis walking guided tour
18:00 – 19:30 Free time in Ermoupolis
19:30 Return to the Conference venue
20:30 – 00:00 Farewell Party
Sunday 29 September 2024
08:30 – 10:00 Breakfast
10:00 – 12:00 SESSION 5 – Moderator: George P. Patrinos
10:00 – 10:30: Best abstract presentations
BA1. Antidepressant Drug Switching in the Swiss population with a focus on Escitalopram and pharmacogenetically relevant drugs: A drug utilization study using the Helsana Database
M. Roth, N.L Wittwer, C.R. Meier, C.A. Huber, H.E. Meyer zu Schwabedissen, M.L. Lampert, S. Allemann, C. Schneider
BA2. Spontaneous human CD8 T cell and EAE-inducible human CD4/CD8 T cell lesions in the brain and spinal cord of HLA-DRB1*15-positive MS PBMC humanized mice
Irini Papazian, Maria Kourouvani, Anastasia Dagkonaki, Vasileios Gouzouasis, Lila Dimitrakopoulou, Nikolaos Markoglou, Fotis Badounas, Theodore Tselios, Maria Anagnostouli, Lesley Probert
10:30 – 11:15 Workshop 6
Career development session: Building a career in genomic medicine
Branka Zukic, Diego Forero, George P. Patrinos, Marc S. Williams
11:15 – 12:15 Keynote lecture 4:
Marc S. Williams – Geisinger, Danville, PA, USA
Using the Genomic Sequence to Shorten the Diagnostic Odyssey: The Real-time Genetic Diagnosis Project
12:15 – 12:30 Summer school conclusions
Meeting adjourns
Please download the document providing some useful logistics information from the following link
We thank the following academic, charitable and corporate entities for generously supporting this event.
Grand sponsor
Gold sponsors
Silver sponsors
Sponsors
Communication sponsors
Registration fees *
Double room: 840 EUR per person
Single room: 990 EUR
Virtual attendance: 250 EUR
Registration fees include:
Accommodation in a double/single room for the entire duration of the Summer School (4 nights), meals (breakfast, coffee breaks, lunches, dinners, welcome reception and social event), educational material, and social activities.
Registration fees *
Double room: 840 EUR per person
Single room: 990 EUR
Virtual attendance: 300 EUR
Registration fees include:
Accommodation in a double/single room for the entire duration of the Summer School (4 nights), meals (breakfast, coffee breaks, lunches, dinners, welcome reception and social event), educational material, and social activities.