2010 Golden Helix Symposium Venue

The venue of the 2010 Golden Helix Symposium is the DIVANI Acropolis Palace hotel*****.

Divani Palace Acropolis Hotel in Athens is a testimony to a fascinating history. Entwining old and new, this simply irresistible luxury hotel in Athens, sits just below the shadow of Acropolis, moments away from the old quarter of Plaka, the brand new archaeological Museum of Acropolis and the well known Herodion theatre.

The Athens Acropolis hotel due to its ideal location combines comfort and classic elegance offering a memorable luxury accommodation in Athens to its guests.

Organizing committee
George P. Patrinos; University of Patras, Department of Pharmacy, Patras, Greece

Federico Innocenti; University of Chicago, Department of Medicine, Chicago, IL, USA

Paolo Fortina; Thomas Jefferson University, Philadelphia, PA, USA

Nancy Cox; University of Chicago, Department of Medicine, Chicago, IL, USA

Invited Speakers

Wilhelm Ansorge (Lausanne, CH)
Aglaia Athanassiadou (Patras, GR)
Nigel Carter (Hinxton, UK)
Jean-Jacques Cassiman (Leuven, BE)
Gianpiero Cavalleri (Dublin, IRL)
Nancy Cox (Chicago, IL, USA)
Johan den Dunnen (Leiden, NL)
Radoje Drmanac (Mountain View, CA, USA)
Beverly Emanuel (Philadelphia, PA, USA)
Paolo Fortina (Philadelphia, PA, USA)
Frank Grosveld (Rotterdam, NL)
Federico Innocenti (Chicago, IL, USA)
Thomas Joos (Tubingen, DE)
Eric Knudsen (Philadelphia, PA, USA)
Larry Kricka (Philadelphia, PA, USA)
Alexander Lezhava (Yokohama, JP)
Cedric le Caignec (Nantes, FR)
Lucio Luzzatto (Toscane, IT)
Joannis Mytilineos (Ulm, DE)
George P. Patrinos (Patras, GR)
Michael B. Petersen (Athens, GR)
Christian Stoeckert (Philadelphia, PA, USA)
Graham Taylor (Leeds, UK)
Jan Traeger-Synodinos (Athens, GR)
Athanassios Tsiatis (Baltimore, MD, USA)
Ron van Schaik (Rotterdam, NL)
Bauke Ylstra (Amsterdam, NL)

Scientific Program

Day 1 – Wednesday, December 1st, 2010

15:00-19:30: DELEGATE REGISTRATION

20:00: WELCOME COCKTAIL

Day 2 – Thursday, December 2nd, 2010

08:30-08:45: Opening addresses

SESSION 1 OMICS, Chairpersons: G. Chrousos, E. Kanavakis

08:45-09:15: Erik Knudsen (Philadelphia, PA, USA)

Transcription and microRNA profiling

09:15-09:45: Nancy Cox (Chicago, IL, USA)

Genome-wide association studies for complex traits

1st Keynote lecture

09:45-10:30: Jean-Jaques Cassiman (Leuven, BE) – Policies and guidelines for genetic testing

COFFEE BREAK

10:45-11:15: George P. Patrinos (Patras, GR)

Unraveling the molecular mechanism of human fetal globin gene silencing

11:15-11:45: Gianpiero Cavalleri (Dublin, IE)

Genetic mapping in epilepsy predisposition and treatment

11:45-12:15: Larry Kricka (Philadelphia, PA, USA)

Consumer Genomics

11:45-12:15: Kevin Long (Chapel Hill, NC, USA)

Population-ized medicine: The PGENI project

LUNCH BREAK WORKSHOP (Sponsored by Agilent Technologies)

COMPANY LECTURES I

14:00-14:30: Mark Ross (Illumina)

Characterizing somatic mutations in cancer genomes using Illumina sequencing

14:30-14:50: Marco L. Pirotta (Life Technologies)

Advances in next-generation sequencing

COFFEE BREAK

15:15-16:30: POSTER SESSION I

SESSION 2 Molecular Cytogenetics, Chairpersons: B. Ylstra, N. Cox

16:30-17:00: Nigel Carter (Hinxton, UK)

Molecular Cytogenetics

17:00-17:30: Bauke Ylstra (Amsterdam, NL)

Molecular cytogenetics in oncology: From technique to therapeutic target

17:00-17:30: Beverly Emanuel (Philadelphia, PA, USA)

Copy Number Variation: cause and susceptibility factor for recurrent genomic disorders

17:30-18:00: Cedric Le Caignec (Nantes, FR)

Application of oligoarray CGH in the diagnostic genetic laboratory

WINE TASTING EVENT (By invitation only)

Day 3 – Friday, December 3rd, 2010

SESSION 3 Next generation sequencing applications, Chairpersons: P. Fortina, G. Patrinos
08:45-09:15: Paolo Fortina (Philadelphia, PA, USA)

Overview of next-generation sequencing technologies

09:15-09:45: Frank Grosveld (Rotterdam, NL)

Next generation sequencing application in the study of transcription

2nd Keynote lecture

09:45-10:30: Lucio Luzzatto (Florence, IT) The rate of somatic mutations and the development of cancer

COFFEE BREAK

10:45-11:15: Radoje Drmanac (Mountain View, CA, USA)

Next-generation sequencing applications: Towards a 1000$ genome

11:15-11:45: Graham Taylor (Leeds, UK)

Next-generation DNA sequencing in the clinic

11:45-12:15: Christian Stoeckert (Philadelphia, PA, USA)

Bioinformatics: Making sense of genomics data

12:15-12:45: Johan den Dunnen (Leiden, NL)

Pathogenic or not – the value of gene variant databases

LUNCH BREAK

COMPANY LECTURES II

14:20-14:40: Rick Hockett (Affymetrix)

The DMET platform

COFFEE BREAK

15:00-16:00: POSTER SESSION II

SESSION 4 Current genetic technology in diagnostics and therapy, Chairpersons: J. den Dunnen, G. Taylor

16:00-16:30: Johan den Dunnen (Leiden, NL)

High resolution melting curve analysis

16:30-17:00: Athanassios Tsiatis (Baltimore, MD, USA)

Pyrosequencing: Application to cancer diagnostics and epigenetic studies

17:00-17:30: Thomas Joos (Tubingen, DE)

Application of proteomics in disease diagnostics

17:30-18:00: Aglaia Athanassiadou (Patras, GR)

Episomal DNA as vector for gene therapy

Evening free

Day 4 – Saturday, December 4th, 2010

SESSION 5 Translating genetic analysis into clinical practice, Chairpersons: F. Innocenti, R. van Schaik
08:45-09:15: Ron van Schaik (Rotterdam, NL)

Implementation of Pharmacogenetics in clinical diagnostics: Results from 5 year experience

09:15-09:45: Sandra Kirkwood-Close (USA)

Pharmacogenomics clinical trials

09:45-10:15: Philippos Patsalis (Nicosia, CY)

FoSTeS/MMBIR and NAHR at the human proximal Xp region and the mechanisms of human Xq isochromosome formation

COFFEE BREAK

COMPANY LECTURES III

10:30-11:00: Ruth Burton (Oxford Gene Technology)

The latest developments in aCGH from OGT

11:00-11:30: Maria Tzeti (Agilent Technologies)

11:30-12:00: Joannis Mytilineos (Ulm, DE)

Immunogenetics

11:00-11:30: Jan Traeger-Synodinos (Athens, GR)

Prenatal, non-invasive and pre-implantation genetic diagnosis of inherited disorders: Lessons from hemoglobinopathies

11:30-12:00: Michael B. Petersen (Athens, GR)

Prognostic markers for complex diseases: The paradigm for non-syndromic deafness

Session 6 – Best abstracts presentation, Chairperson: George P. Patinos

13:00-13:10: Alexander Lezhava (Yokohama, JP)

Two-colour SNP genotyping of genes involved in warfarin dose adjustement

13:10-13:20: Marianna Bei (Charlstown, MA, USA)

Pathways controlling epithelial appendage formation

13:20-13:30: Mike Makrigiorgos (Boston, MA, USA)

Replacing PCR with COLD-PCR technology enriches variant DNA sequences and redefines the sensitivity of mutation analysis

Closing Remarks and Future Meetings

MEETING ENDS

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