Introduction
21st Golden Helix Pharmacogenomics Day
Biopolis
7 August 2018, Singapore
The 21st Golden Helix Pharmacogenomics Day will be organized in Singapore. The meeting will be co-organized from the Golden Helix Foundation and the Surveillance and Pharmacogenomics Initiative for Adverse Drug Reactions (SAPhIRE) Network and will be held at the Breakthrough Theaterette (Level 4, Matrix Building, Biopolis, Singapore).
This international event is open for biomedical scientists, hospital and general pharmacists, specialists, general practitioners, medical students, laboratory technicians, regulators, healthcare insurers and others interested in pharmacogenomics.
The meeting will feature lectures from local and international speakers on the impact of pharmacogenomics in various medical specialties, focusing in particular on the bioinformatics solutions in pharmacogenomics.
Under the auspices of:
About SAPhIRE
About SAPhIRE
The Surveillance and Pharmacogenomics Initiative for Adverse Drug Reactions (SAPhIRE) program is funded by the Biomedical Research Council (BMRC) of A*STAR, Singapore to improve drug safety by developing an active surveillance network for adverse drug reaction (ADR) monitoring and discovery of genomic biomarkers that are predictive of specific ADRs. This programme brings together expertise from research institutes, universities, hospitals and the Health Science Authority of Singapore to advance pharmacogenomics in our region. For additional information, please visit the SAPhIRE website.
Speakers
Organizing Committee
Michael Winther, Associate Director, Genome Institute of Singapore, Singapore, SG
Wasun Chantratita, Professor, Ramathibodi Hospital, Bangkok, Thailand
Le Thi Ly, Associate Professor,International University, Vietnam National University, Ho Chi Minh City, Vietnam
George P. Patrinos, Associate Professor, University of Patras, Department of Pharmacy, Patras, Greece
Invited Speakers
James Best, Singapore, SG
Alexandre Chan, Singapore, SG
Wasun Chantratita, Bangkok, TH
Jian Jin Liu, Singapore, SG
Teri Manolio, Baltimore, MD, USA
Taisei Mushiroda, Yokohama, JP
Leong Khai Pang, Singapore, SG
George P. Patrinos, Patras, GR
Jae-Gook Shin, Busan, KR
Chonlaphat Sukasem, Bangkok, TH
Cynthia Sung, Singapore, SG
Patrick Tan, Singapore, SG
Steven Turner, Singapore, SG
Hwee Lin Wee, Singapore, SG
Scientific Program
Scientific Program
08:00 – 09:00 Registration
Session I: Advances in Pharmacogenomics Research
09:00 – 09:15 Opening address
Michael Winther, Associate Director, Genome Institute of Singapore, Singapore, SG
09:15 – 09:30 The NIH Initiatives in Pharmacogenomics
Teri Manolio, Director, Division of Genomic Medicine, NHGRI/NIH, Baltimore, MD, USA
09:30 – 10:00 Setting the Scene: Incidence of ADRs in Hospitals
Alexandre Chan, Associate Professor, Department of Pharmacy, National University of Singapore, Singapore
10:00 – 10:30 Use of Algorithms for the Detection of Adverse Drug Reactions
Cynthia Sung, Adjunct Associate Professor, Duke University and National University of Singapore; Regulatory Consultant, Health Sciences Authority, Singapore
10:30 – 11:15 Coffee break – Poster and Industry presentations
Session II: Translation from Laboratory to the Clinic
11:15 – 11:45 Discovery and Validation of Biomarkers for ADRs
Jian Jun Liu, Deputy Executive Director and Senior Group Leader, Genome Institute of Singapore, A*STAR, Singapore
11:45 – 12:012 CPIC and other Guidelines for PGx Implementation
Chonlaphat Sukasem, Associate Professor and Head, Devision of Pharmacogenomics and Personalised Medicine, Ramathibodi hospital, Mahidol University, Bangkok, Thailand
12:12 – 12:45 Economics justification for a pre-emptive pharmacogenetics clinical service
Hwee Lin Wee, Assistant Professor, Saw Swee Hock School of Public Health, National University of Singapore, Singapore
12:45 – 13:45 Lunch Break
Session III: Regional Updates on Pharmacogenomics
13:45 – 14:15 Clinical Implementation of pharmacogenomics: Issues and perspectives
Jae-Gook Shin, Professor, Pharmacology/Clinical Pharmacology, Inje University, Seoul, Korea
14:15 – 14:45 Pharmacogenomics: European Perspectives
George P. Patrinos, Associate Professor, University of Patras, Department of Pharmacy, Patras, Greece
14:45 – 15:15 Pharmacogenomics Research in South East Asia
Taisei Mushiroda, Team Leader, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
15:15 – 16:00 Coffee Break - Poster Presentations
Session IV: Precision Medicine and Pharmacogenomics
16:00 – 16:30 Developing a National Precision Medicine Programme
Patrick Tan, Professor, Duke-NUS Medical School, Deputy Executive Director, BMRC (A*STAR), Singapore
16:30 – 17:00 Pharmacogenomics Implementation in South East Asia
Wasun Chantratita, Professor and Head, Center for Medical Genomics, Faculty of Medicine, Ramathibodi Hospital Mahidol University, Bangkok, Thailand
17:00 – 17:30 Pharmacogenomics and the real world of clinical practice
James Best, Dean, LKC Medicine, Singapore
17:30 Closing address
Satellite event
7th SEAPharm meeting
Organizing Committee
Michael Winther, Associate Director, Genome Institute of Singapore, Singapore, SG
Le Thi Ly, Associate Professor, International University, Vietnam National University, Ho Chi Minh City, Vietnam
SEAPharm Speakers (partial list)
Chonlaphat Sukasem, Bangkok, TH
Taisei Mushiroda, Yokohama, JP
Wasun Chantratita, Bangkok, TH
Surakameth Mahasirimongkol, Bangkok, TH
Wichittra Tassaneeyakul, Koen Kaen, TH
Usa Chaikledkaew, Bangkok, TH
Hwee Lin Wee, Singapore, SG
Co-chairs: Michael Winther, Ly Thi Ly
09:00 – 09:30 Opening Remarks
Michael Winther, Associate Director, Genome Institute of Singapore, A*STAR Singapore
Le Thi Ly, Associate Professor, International University, Vietnam National University, Ho Chi Minh City, Vietnam
Session 1: 100 Pharmacogene Project
09:30 – 10:00 Overview of 100 Pharmacogene Project
Wasun Chantratita, Professor, Ramathibodi Hospital, Bangkok, Thailand
10:00 – 10:30 Protocol for Sample Collection, Processing and Analysis
Taisei Mushiroda, Group Director, RIKEN Institute, Yokohama, Japan
10:30 – 11:00 Current Status and Next Steps
Updates from all participating countries
11:00 – 11:15 Coffee break
11:15 – 11:45 Updates from Global Pharmacogenomics Leadership Summit
Wasun Chantratita, Professor, Ramathibodi Hospital, Bangkok, Thailand
Michael Winther, Associate Director, Genome Institute of Singapore, A*STAR Singapore
11:45 – 12:30 Developing Clinical Recommendations for Southeast Asia
Michael Winther, Associate Director, Genome Institute of Singapore, A*STAR Singapore
Surakameth Mahasirimongkol, Physician, Ministry of Public Health, Thailand
12:30 – 13:30 Lunch Break
Session 2: SEAPharm Collaborative Studies
13:30 – 14:15 Pharmacogenomics of Severe Cutaneous Adverse Reactions (SCARs)
Chonlaphat Sukasem, Associate Professor, Mahidol University, Bangkok, Thailand
Surakameth Mahasirimongkol, Physician, Ministry of Public Health, Thailand
Wichittra Tassaneeyakul, Head of Department, Koen Kaen University, Thailand
14:15 – 15:00 Feasibility and Health Economics of HLA Genotyping to Prevent SJS/TEN
Hwee Lin Wee, Assistant Professor, National University of Singapore, Singapore
Usa Chaikledkaew, Associate Professor, Mahidol University, Bangkok, Thailand
15:00 – 15:30 Pharmacogenomics of HIV Therapeutics
Chonlaphat Sukasem, Associate Professor, Mahidol University, Bangkok, Thailand
15:30 – 16:00 Coffee Break
16:00 – 17:00 Updates from SEAPharm members
Brief updates from all SEAPharm attendees from member countries
17:00 – 18:00 SEAPharm Survey Results, Future Collaboration and 8th SEAPharm (2019)
Wasun Chantratita, Professor, Ramathibodi Hospital, Bangkok, Thailand
Surakameth Mahasirimongkol, Physician, Ministry of Public Health, Thailand
19:00 Dinner for invited guests and speakers
Registration
Registration
The registration for this event is closed.
