The 6th U-PGx Personalized Medicine Day will be organized in Athens, Greece on December 13th, 2019.
The meeting will be co-organized by the Golden Helix Foundation and the University of Patras, both partners of the Ubiquitous Pharmacogenomics (U-PGx) project, funded by the European Commission (H2020-668353). The meeting will be held in the majestic Zappeion Mansion conference hall. This international event is open for clinical pharmacologists, hospital pharmacists, general pharmacists, specialists, general practitioners, medical students, laboratory technicians, regulators, healthcare insurers and others interested in pharmacogenomics.
On behalf of the Organizing Committee
This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 668353.
Clinical application of pharmacogenomics knowledge will result in less ‘trial and error’ prescribing and more efficacious, safer and cost-effective drug therapy. However, despite the major advances in pharmacogenomics and several commercially available pharmacogenomics tests, its application in routine patient care remains very limited. The U-PGx consortium will address major challenges and obstacles for implementation of pharmacogenomics testing in patient care, taking into account the diversity of healthcare systems and citizens across Europe. Specifically, U-PGx will investigate if the emerging approach of pre-emptive genotyping of an entire panel of important pharmacogenomics markers is cost-effective and results in a better outcome for patients. With the pre-emptive pharmacogenomics testing approach data on multiple important pharmacogenes are collected prospectively and embedded into the patients’ electronic record. Typically, it alerts prescribers and pharmacists through electronic clinical decision support systems when a drug is ordered or dispensed for a patient with an at-risk genotype. The new model of personalised medicine through pre-emptive pharmacogenomics testing will be conducted at a large scale in seven existing European health care environments in the Netherlands, Spain, UK, Italy, Austria, Greece, and Slovenia.
George P Patrinos (Patras, Greece)
Magnus Ingelman-Sundberg (Stockholm, Sweden)
Ana Alfirevic (Liverpool, UK)
Vita Dolzan (Ljubljiana, SI)
Magnus Ingelman-Sundberg (Stockholm, SE)
Federico Innocenti (Chapel Hill, NC, USA)
Lidija Konta (Frankfurt, DE)
George P. Patrinos (Patras, GR)
Jesse Swen (Leiden, NL)
Daniela Steinberger (Frankfurt, DE)
Ron H. van Schaik (Rotterdam, NL)
08:00 - 09:30 Registration
09:30 - 09:45 Opening statements
Chair: Prof. George P. Patrinos
09:45 – 10:15 Magnus Ingelman-Sundberg, Professor, Karolinska Institutet, Stockholm, Sweden
Novel methods for the characterisation of the influence of Pharmacogenomic variants in drug action
10:15 – 10:45 Jesse Swen, Associate Professor, Leiden University Medical Center, Leiden, the Netherlands
The Ubiquitous Pharmacogenomics project
10:45 – 11:15 George P. Patrinos, Professor, University of Patras, Department of Pharmacy, Patras, Greece
Pharmacogenomics and Public Health: The path to integrate pharmacogenomics in the clinic
11:15 – 12:30 Prof. Dr. Daniela Steinberger, Dr. Lidija Konta, Biologis, Frankfurt, Germany
Overcoming the obstacles for pharmacogenomics: The solutions for clinical implementation are here now.
12:30 – 14:00 Lunch break
Chair: Prof. Magnus Ingelman-Sundberg
14:00 – 14:30 Ron H. van Schaik, Professor, Erasmus University Medical Center, Department of Clinical Chemistry, Rotterdam, the Netherlands
Experiences in implementing Pharmacogenomics in clinical practice: Do You have your DNA passport?
14:30 – 15:00 Federico Innocenti, Associate Professor and Associate Director, Center for Pharmacogenomics and Individualized Therapy, University of North Carolina, Chapel Hill, NC, USA
Clinical trials network for cancer drug development and the opportunities they offer
15:00 –15:30 Ana Alfirevic, Professor, University of Liverpool, Liverpool, UK
Implementation of genetic biomarkers in National Health Services - the NHS England experience
15:30 – 16:00 Coffee break
16:00 – 17:15 Round table discussion
Panel: Magnus Ingelman-Sundberg (coordinator), Ron van Schaik, George P. Patrinos, Vita Dolzan, Federico Innocenti, Ana Alfricevic
17:15 – 17:30 Concluding remarks