Introduction
12th Golden HelixPharmacogenomics Day
Auditorium, Centro di Riferimento Oncologico
6 December 2013, Aviano, Italy
The 12th Golden Helix Pharmacogenomics day was held in the Auditorium of the Centro di Riferimento Oncologico (CRO) in Aviano, Italy. The meeting included speakers and participants from various Italian cities and also from other countries, such as the USA, Netherlands, Slovenia, and focused on pharmacogenomics in cancer treatment. Meeting participants, who excedded 130, were awarded credits for continuous medical education (CME).
Organized by:
Under the auspices of:
Speakers
Organizing Committe
Giuseppe Toffoli; Researcher, Centro di Riferimento Oncologico, National Cancer Center, Aviano, Italy
Federico Innocenti; Associate Professor and Associate Director, University of North Carolina, Chapel Hill, NC, United States of America
George P. Patrinos; Associate Professor, University of Patras, Department of Pharmacy, Patras, Greece
Invited speakers
Giuseppe Aprile (Udine, Italy)
Emilio Bria (Verona, Italy)
Romano Danesi, (Pisa, Italy)
Vita Dolzan (Ljubljana, Slovenia)
Henk-Jan Guchelaar (Leiden, the Netherlands)
Federico Innocenti (Chapel Hill, NC, USA)
Mita Mancini (London, UK)
Enrico Mini (Florence, Italy)
Giorgio Minotti (Rome, Italy)
Giuseppe Novelli (Rome, Italy)
Arianna Paganelli (Jesi, Italy)
George P. Patrinos (Patras, Greece)
Mario Scartozzi (Ancona, Italy)
Giuseppe Toffoli (Aviano, Italy)
Miro Venturi (Basel, Switzerland)
Marina Ziche (Siena, Italy)
Scientific Program
Scientific Program
08.30 09.00 Registration
09.00 09.20 Opening addresses
Session 1 - Chairpersons: Romano Danesi, Giuseppe Novelli
09.20 09.50 Federico Innocenti, Associate Professor, University of North Carolina, Chapel Hill, NC, USA
Personalizing care in cancer
09.50 10.20 Giuseppe Toffoli, Group Leader, Centro di Riferimento Oncologico, Aviano, Italy
Application of pharmacogenomics in clinical trials
10.20 10.40 George P. Patrinos, Associate Professor, University of Patras Department of Pharmacy, Patras, Greece
Pharmacogenomics in developing countries in Europe: Challenges and pitfalls
10.40 11.00 Vita Dolzan, Professor, Ljubljana University Medical School, Ljubljana, Slovenia
Pharmacogenomic biomarkers related to malignant mesothelioma treatment
COFFEE BREAK
11.15 12.45 SIF Symposium: Pharmacogenomics of germ-line genetic variation - Chairperson: Teresita Mazzei
- Romano Danesi, Professor, University of Pisa, Pisa, Italy
Translation of pharmacogenomics to the clinical practice: the fluoropyrimidines model
- Enrico Mini, Professor,University of Florence, Florence, Italy
Colorectal cancer as a model for pharmacogenomics based personalized treatment
- Giorgio Minotti, Professor, Policlinico Universitario, Rome, Italy
Pharmacogenomics markers of drug-induced cardiotoxicity
- Marina Ziche, Professor, University of Siena, Siena, Italy
In vitro strategies for pharmacogenomics markers functional validation
LUNCH BREAK
13.45 14.45 AIOM Symposium: Pharmacogenomics of somatic genetic variation, Chairperson: Giuseppe Altavilla
- Mario Scartozzi, Researcher, University Hospital Riuniti Umberto I, Ancona, Italy
The value of somatic mutations testing in stomach cancer
- Giuseppe Aprile, Researcher, University Hospital, Udine, Italy
The value of somatic mutations testing in colorectal cancer
- Emilio Bria, Researcher, University Hospital, Verona, Italy
The value of somatic mutations testing in lung cancer
Session 2 - Chairpersons: Giuseppe Toffoli, Federico Innocenti
14.45 15.45 Giuseppe Novelli, Professor and Rector, Policlinico Tor Vergata, Rome, Italy
Guidance and regulatory needs for pharmacogenomics testing in the clinical practice: AIFA and EMA perspectives
15.45 16.30 Henk-Jan Guchelaar, Professor, Leiden University Medical Center, Leiden, the Netherlands
Prospective pharmacogenetic analysis to guide therapy: The Leiden experience
16.30 17.30 - Satellite Workshop outside of ECM program: Companies point of view on the pharmacogenomics
- Miro Venturi, Clinical Specialist, Ho_mann La Roche, Basel, Switzerland
Personalized medicine approaches in the discovery and development of new drugs: Point of view of the pharma companies
- Arianna Paganelli, Specialist, Diatech, Jesi, Italy
Nanostring: a quick and reliable tool for diagnostics and translational research
- Mita Mancini, Clinical Specialist, A_ymetrix Central Europe UK, Ltd
DMET+ Solution: bringing pharmacogenetics into clinical practice
17.30 17.45 Discussion - Concluding remarks
