Welcome
2010 Golden Helix Symposium
"Genetic Analysis in Translational Medicine"
DIVANI Acropolis Palace hotel, 1-4 December 2010, Athens, Greece
Under the aurpices of His Excellency the President of the Hellenic Republic Dr. Karolos Papoulias
We are very pleased to welcome you to the 2010 GOLDEN HELIX Symposium: Genetic Analysis in Translational Medicine. Recognizing the challenges that currently emerge for molecular medicine in the post-genomic era, the GOLDEN HELIX Symposium on Genetic Analysis and Translational Medicine includes lectures by more than 20 internationally renowned scientists in the field.
The scientific program covers all aspects of this discipline, including Genome-wide Association Studies, Genomics of cancer and human disorders, Molecular Cytogenetics, Genomic technology, next-generation sequencing, Pharmacogenomics, Bioinformatics, Genetics and Society and Genetic analysis in clinical practice.
We are committed to setting the highest standard symposia in the field of human genomics and personalised medicine, and look forward to a very successful meeting.
The 2010 Golden Helix Symposium Organizing Committee
Organized by:
Endorsed by:
Venue
2010 Golden Helix Symposium Venue
The venue of the 2010 Golden Helix Symposium is the DIVANI Acropolis Palace hotel*****.
Divani Palace Acropolis Hotel in Athens is a testimony to a fascinating history. Entwining old and new, this simply irresistible luxury hotel in Athens, sits just below the shadow of Acropolis, moments away from the old quarter of Plaka, the brand new archaeological Museum of Acropolis and the well known Herodion theatre.
The Athens Acropolis hotel due to its ideal location combines comfort and classic elegance offering a memorable luxury accommodation in Athens to its guests.
Speakers
Organizing committee
George P. Patrinos; University of Patras, Department of Pharmacy, Patras, Greece
Federico Innocenti; University of Chicago, Department of Medicine, Chicago, IL, USA
Paolo Fortina; Thomas Jefferson University, Philadelphia, PA, USA
Nancy Cox; University of Chicago, Department of Medicine, Chicago, IL, USA
Invited Speakers
Wilhelm Ansorge (Lausanne, CH)
Aglaia Athanassiadou (Patras, GR)
Nigel Carter (Hinxton, UK)
Jean-Jacques Cassiman (Leuven, BE)
Gianpiero Cavalleri (Dublin, IRL)
Nancy Cox (Chicago, IL, USA)
Johan den Dunnen (Leiden, NL)
Radoje Drmanac (Mountain View, CA, USA)
Beverly Emanuel (Philadelphia, PA, USA)
Paolo Fortina (Philadelphia, PA, USA)
Frank Grosveld (Rotterdam, NL)
Federico Innocenti (Chicago, IL, USA)
Thomas Joos (Tubingen, DE)
Eric Knudsen (Philadelphia, PA, USA)
Larry Kricka (Philadelphia, PA, USA)
Alexander Lezhava (Yokohama, JP)
Cedric le Caignec (Nantes, FR)
Lucio Luzzatto (Toscane, IT)
Joannis Mytilineos (Ulm, DE)
George P. Patrinos (Patras, GR)
Michael B. Petersen (Athens, GR)
Christian Stoeckert (Philadelphia, PA, USA)
Graham Taylor (Leeds, UK)
Jan Traeger-Synodinos (Athens, GR)
Athanassios Tsiatis (Baltimore, MD, USA)
Ron van Schaik (Rotterdam, NL)
Bauke Ylstra (Amsterdam, NL)
Scientific Program
Scientific Program
Day 1 - Wednesday, December 1st, 2010
15:00-19:30: DELEGATE REGISTRATION
20:00: WELCOME COCKTAIL
Day 2 - Thursday, December 2nd, 2010
08:30-08:45: Opening addresses
SESSION 1 OMICS, Chairpersons: G. Chrousos, E. Kanavakis
08:45-09:15: Erik Knudsen (Philadelphia, PA, USA)
Transcription and microRNA profiling
09:15-09:45: Nancy Cox (Chicago, IL, USA)
Genome-wide association studies for complex traits
1st Keynote lecture
09:45-10:30: Jean-Jaques Cassiman (Leuven, BE) - Policies and guidelines for genetic testing
COFFEE BREAK
10:45-11:15: George P. Patrinos (Patras, GR)
Unraveling the molecular mechanism of human fetal globin gene silencing
11:15-11:45: Gianpiero Cavalleri (Dublin, IE)
Genetic mapping in epilepsy predisposition and treatment
11:45-12:15: Larry Kricka (Philadelphia, PA, USA)
Consumer Genomics
11:45-12:15: Kevin Long (Chapel Hill, NC, USA)
Population-ized medicine: The PGENI project
LUNCH BREAK WORKSHOP (Sponsored by Agilent Technologies)
COMPANY LECTURES I
14:00-14:30: Mark Ross (Illumina)
Characterizing somatic mutations in cancer genomes using Illumina sequencing
14:30-14:50: Marco L. Pirotta (Life Technologies)
Advances in next-generation sequencing
COFFEE BREAK
15:15-16:30: POSTER SESSION I
SESSION 2 Molecular Cytogenetics, Chairpersons: B. Ylstra, N. Cox
16:30-17:00: Nigel Carter (Hinxton, UK)
Molecular Cytogenetics
17:00-17:30: Bauke Ylstra (Amsterdam, NL)
Molecular cytogenetics in oncology: From technique to therapeutic target
17:00-17:30: Beverly Emanuel (Philadelphia, PA, USA)
Copy Number Variation: cause and susceptibility factor for recurrent genomic disorders
17:30-18:00: Cedric Le Caignec (Nantes, FR)
Application of oligoarray CGH in the diagnostic genetic laboratory
WINE TASTING EVENT (By invitation only)
Day 3 - Friday, December 3rd, 2010
SESSION 3 Next generation sequencing applications, Chairpersons: P. Fortina, G. Patrinos
08:45-09:15: Paolo Fortina (Philadelphia, PA, USA)
Overview of next-generation sequencing technologies
09:15-09:45: Frank Grosveld (Rotterdam, NL)
Next generation sequencing application in the study of transcription
2nd Keynote lecture
09:45-10:30: Lucio Luzzatto (Florence, IT) The rate of somatic mutations and the development of cancer
COFFEE BREAK
10:45-11:15: Radoje Drmanac (Mountain View, CA, USA)
Next-generation sequencing applications: Towards a 1000$ genome
11:15-11:45: Graham Taylor (Leeds, UK)
Next-generation DNA sequencing in the clinic
11:45-12:15: Christian Stoeckert (Philadelphia, PA, USA)
Bioinformatics: Making sense of genomics data
12:15-12:45: Johan den Dunnen (Leiden, NL)
Pathogenic or not - the value of gene variant databases
LUNCH BREAK
COMPANY LECTURES II
14:20-14:40: Rick Hockett (Affymetrix)
The DMET platform
COFFEE BREAK
15:00-16:00: POSTER SESSION II
SESSION 4 Current genetic technology in diagnostics and therapy, Chairpersons: J. den Dunnen, G. Taylor
16:00-16:30: Johan den Dunnen (Leiden, NL)
High resolution melting curve analysis
16:30-17:00: Athanassios Tsiatis (Baltimore, MD, USA)
Pyrosequencing: Application to cancer diagnostics and epigenetic studies
17:00-17:30: Thomas Joos (Tubingen, DE)
Application of proteomics in disease diagnostics
17:30-18:00: Aglaia Athanassiadou (Patras, GR)
Episomal DNA as vector for gene therapy
Evening free
Day 4 - Saturday, December 4th, 2010
SESSION 5 Translating genetic analysis into clinical practice, Chairpersons: F. Innocenti, R. van Schaik
08:45-09:15: Ron van Schaik (Rotterdam, NL)
Implementation of Pharmacogenetics in clinical diagnostics: Results from 5 year experience
09:15-09:45: Sandra Kirkwood-Close (USA)
Pharmacogenomics clinical trials
09:45-10:15: Philippos Patsalis (Nicosia, CY)
FoSTeS/MMBIR and NAHR at the human proximal Xp region and the mechanisms of human Xq isochromosome formation
COFFEE BREAK
COMPANY LECTURES III
10:30-11:00: Ruth Burton (Oxford Gene Technology)
The latest developments in aCGH from OGT
11:00-11:30: Maria Tzeti (Agilent Technologies)
11:30-12:00: Joannis Mytilineos (Ulm, DE)
Immunogenetics
11:00-11:30: Jan Traeger-Synodinos (Athens, GR)
Prenatal, non-invasive and pre-implantation genetic diagnosis of inherited disorders: Lessons from hemoglobinopathies
11:30-12:00: Michael B. Petersen (Athens, GR)
Prognostic markers for complex diseases: The paradigm for non-syndromic deafness
Session 6 - Best abstracts presentation, Chairperson: George P. Patinos
13:00-13:10: Alexander Lezhava (Yokohama, JP)
Two-colour SNP genotyping of genes involved in warfarin dose adjustement
13:10-13:20: Marianna Bei (Charlstown, MA, USA)
Pathways controlling epithelial appendage formation
13:20-13:30: Mike Makrigiorgos (Boston, MA, USA)
Replacing PCR with COLD-PCR technology enriches variant DNA sequences and redefines the sensitivity of mutation analysis
Closing Remarks and Future Meetings
MEETING ENDS
Gallery
https://goldenhelix.org/conferences/symposia/previous-symposia/294-2010-golden-helix-symposium#sigProId1147f22b3a